15 résultats pour "antibodies"
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Immune System.
The humoral immune response involves a complex series of events after antigens enter the body. First, macrophages take up some of the antigen and attach it to classII MHC molecules, which then present the antigen to T helper cells. The T helper cells bind the presented antigen, which stimulates the T helper cells to divide andsecrete stimulatory molecules called interleukins. The interleukins in turn activate any B lymphocytes that have also bound the antigen. The activated B cells then divide...
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Blood.
substances. For example, a person who is blood type A positive will not make antibodies against the A or Rh markers, but will make antibodies against the B marker,which is not on that person’s own red blood cells. If blood containing the B marker (from types B positive, B negative, AB positive, or AB negative) is transfused into thisperson, then the transfused red blood cells will be rapidly destroyed by the patient’s anti-B antibodies. In this case, the transfusion will do the patient no good a...
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Leukemia.
leukemia, and normal or mildly decreased in chronic lymphocytic leukemia. Nearly all chronic leukemia patients have increased white cell counts. In chronic myelocyticleukemia, some of these leukemic white cells are capable of functioning as normal cells do by fighting infectious microbes. Hence, infection is no more common than in ahealthy individual. In chronic lymphocytic leukemia the blood contains large numbers of malignant lymphocytes that do not function normally. Normal lymphocytescoexist...
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Bacteria - biology.
A2 b Bacterial Killers Some dramatic infectious diseases result from exposure to bacteria that are not part of our normal bacterial community. Cholera, one of the world’s deadliest diseasestoday, is caused by the bacterium Vibrio cholerae . Cholera is spread in water and food contaminated with the bacteria, and by people who have the disease. After entering the body, the cholera bacteria grow in the intestines, often along the surface of the intestinal wall, where they secrete a toxin (poiso...
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Protein.
Myosin, the protein chiefly responsible for muscle contraction, combines with actin, another muscle protein, forming actomyosin, the different filaments of whichshorten, causing the contracting action. VI GLOBULAR PROTEINS Unlike fibrous proteins, globular proteins are spherical and highly soluble. They play a dynamic role in body metabolism. Examples are albumin, globulin, casein,hemoglobin, all of the enzymes, and protein hormones. The albumins and globulins are classes of soluble proteins a...
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A simple, sensitive, low-cost assay for SARS-CoV-2 spike protein specific antibodies
A simple, sensitive, low-cost assay for SARS-CoV-2 spike protein-specific antibodies Stephan Menzel1†, Julia Hambach1†, Tobias Stähler1*, Thomas Eden1, Dorte Wendt1, Natalie Tode1, Friedrich Haag1, Eva Tolosa1, Marcus Altfeld1,2, Anahita Fathi3,4,5, Christine Dahlke3,4,5, Marylyn M. Addo3,4,5, Friedrich Koch-Nolte1* 1 2 Department of Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany 3 4 Institute of Immunology, Universi...
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Poliomyelitis.
Physical therapy helps patients with paralytic polio stretch and move affected muscles. This movement minimizes the atrophy, or shrinkage, of affected muscles andlimbs and builds strength. Exercises can also retrain working muscles to compensate for other muscles that have permanently lost the ability to move. Rehabilitativetherapy trains patients to use braces, crutches, and other devices that provide support and aid mobility. V PREVENTION OF POLIO Immunization with polio vaccine is the best w...
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Diabetes Mellitus.
Once diabetes is diagnosed, treatment consists of controlling the amount of glucose in the blood and preventing complications. Depending on the type of diabetes, thiscan be accomplished through regular physical exercise, a carefully controlled diet, and medication. Individuals with Type 1 diabetes must receive insulin, often two to four times a day, to provide the body with the hormone it does not produce. Insulin cannot be takenorally, because it is destroyed in the digestive system. Consequent...
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Anatomy.
The body defends itself against foreign proteins and infectious microorganisms by means of a complex dual system that depends on recognizing a portion of the surfacepattern of the invader. The two parts of the system are termed cellular immunity, in which lymphocytes are the effective agent, and humoral immunity, based on theaction of antibody molecules. When particular lymphocytes recognize a foreign molecular pattern (termed an antigen), they release antibodies in great numbers; other lymphocy...
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Influenza.
days and disappear in seven to ten days. However, coughing and fatigue may persist for two or more weeks. Death from influenza itself is rare. But influenza can aggravate underlying medical conditions, such as heart or lung disease. Invading influenza viruses produceinflammation in the lining of the respiratory tract, damage that increases the risk that secondary infections will develop. Common complications include bronchitis,sinusitis, and bacterial pneumonia, occurring most frequently in olde...
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Kidney.
secretion. An additional function of the kidney is the processing of vitamin D; the kidney converts this vitamin to an active form that stimulates bone development. Several hormones are produced in the kidney. One of these, erythropoietin, influences the production of red blood cells in the bone marrow. When the kidney detectsthat the number of red blood cells in the body is declining, it secretes erythropoietin. This hormone travels in the bloodstream to the bone marrow, stimulating theproducti...
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Acquired Immunodeficiency Syndrome.
child transmission is particularly prevalent in Africa. D Misperceptions About HIV Transmission The routes of HIV transmission are well documented by scientists, but health officials continually grapple with people’s unfounded fears concerning the potential for HIVtransmission by other means. HIV differs from other infectious viruses in that it dies quickly if exposed to the environment. No evidence has linked HIV transmission tocasual contact with an infected person, such as a handshake, huggi...
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Genetic Engineering.
Pseudomonas fluorescens bacterium. The genetically altered Pseudomonas fluorescens bacterium produces light in proportion to the amount of its activity in breaking down the naphthalene, thus providing a way to monitor the efficiency of the process ( see Bioremediation). A3 Medicine In 1982 the United States Food and Drug Administration (FDA) approved for the first time the medical use of a recombinant DNA protein, the hormone insulin, whichhad been cloned in large quantities by inserting th...
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Circulatory System.
C Additional Functions In addition to oxygen, the circulatory system also transports nutrients derived from digested food to the body. These nutrients enter the bloodstream by passingthrough the walls of the intestine. The nutrients are absorbed through a network of capillaries and veins that drain the intestines, called the hepatic portal circulation.The hepatic portal circulation carries the nutrients to the liver for further metabolic processing. The liver stores a variety of substances, suc...
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Cell (biology) - biology.
proteins, or other proteins required by the cell. While relatively simple in construction, prokaryotic cells display extremely complex activity. They have a greater range of biochemical reactions than those found in theirlarger relatives, the eukaryotic cells. The extraordinary biochemical diversity of prokaryotic cells is manifested in the wide-ranging lifestyles of the archaebacteria andthe bacteria, whose habitats include polar ice, deserts, and hydrothermal vents—deep regions of the ocean un...